Transcription: It’s You (Lee Konitz) from Three Guys

Here’s a rough transcription of Steve Swallow, one my favourite bassists, playing on the album Three Guys with Lee Konitz and Paul Motian. (Dreamy band or what?). It’s a Konitz composition over It’s You Or No One. So far, I can’t find it online (tiny sample in this article) but I’m reliably informed it exists on youtube.

Anyway, here is the unison line that ends the tune:

It’s You unison line transcription

It’s You unison line (Eb)

And here it is played in somewhat Swallow-y style — very light roundwounds with a pick and loads of tone rolled off:

Connoisseurs will know that the pick should really be copper, and the bass a semi-acoustic with a piezo somewhere, strung E-C, etc.


Crossing Fields at Central Saint Martins

I have an interest in the relationship between the arts and sciences (see, e.g., here), and today a few of us from the Crick Institute received a guided tour of a nice exhibition at Central Saint Martins. Crossing Fields is a degree show for their almost-unique MA in Art and Science and is well worth a look in the next few days. A few that I managed to get snaps of are below (there are many more fantastic works to see). These ones are by Julie Light, Meri Lahti and Chang Zhou respectively.


Crick Institute Summer Student programme

You don’t need to be a biologist to work at the Crick Institute! I’m not. If you are an undergraduate, here’s a way to sample the life of a biological physicist…

As an undergraduate, I hadn’t considered working in research until I fell into a summer research project with the excellent Mike Evans at Leeds. He actually ended up being my PhD supervisor, but in a broader sense the placement opened my eyes to the process of doing “new stuff”; the feeling that what you’re doing hasn’t been done before is quite a special one.

Anyway, this year I’m part of the Crick’s summer student programme, and have a project open on applying quantitative and physical principles to a biological system. Details can be found here.



Research publication: Roles of Interleaflet Coupling and Hydrophobic Mismatch in Lipid Membrane Phase-Separation Kinetics

At last year’s Biophysical Society 2015 meeting, Peter Olmsted and I met Philip Fowler, who at the time worked in Mark Sansom‘s group (he now works in the Nuffield Department of Medicine at Oxford). I had noticed a signal in their lipid bilayer simulations that looked like a two-step asymmetry/symmetry transition we had studied theoretically. Understanding how constituents of a lipid bilayer interact and self-organise is key to the biology of the cell membrane, as well as to applications of synthetic lipid bilayer membranes.

It has been a pleasure to work with Phil and Mark over the past year as we have looked closely into the symmetry and asymmetry of phase-separating bilayers, using a raft (geddit?) of new simulations expertly constructed and analysed by Phil. A joint paper is out now in JACS, linking the kinetics of lipid bilayer phases to a theoretical model of competing inter-leaflet coupling effects. Check it out!

Roles of Interleaflet Coupling and Hydrophobic Mismatch in Lipid Membrane Phase-Separation Kinetics